Organ medicine is based on the core technology breakthrough of long-term maintenance of detached organs, which maintains their activity and function by supplying blood and oxygen to detached organs, achieving research and treatment of diseases at the organ level. It originated from the innovation of traditional organ transplantation methods, and subsequently emerged on the basis of original technological breakthroughs such as non ischemic organ transplantation, organ isolation treatment, and disease organ drug screening models. It has expanded from organ transplantation to eight major fields including organ teaching, organ donation, organ isolation treatment, organ emergency, organ support research, and organ support, filling the gaps in current medical research and treatment methodology and helping to achieve new breakthroughs in medical research thinking and models. It is expected to produce a number of research results that have not yet been achieved by existing medical research methods, and develop innovative products with broad prospects. Currently, typical products such as non ischemic liver perfusion systems, live organ laparoscopic training systems, and organ donation machines have been incubated.
Organ emergency treatment
Establishing a new emergency mode of "cardiopulmonary liver" resuscitation, successfully restoring isolated pig brain function 30 minutes after cardiac arrest, challenging existing diagnostic criteria for death, providing new ideas for improving emergency success rates in clinical practice, and offering a new platform for neuroscience research. Develop new emergency equipment and create a composite life support system (ex vivo replacement of heart, lung, liver, and kidney functions).
Organ support
Establishing a new technology for extracorporeal liver perfusion support therapy, successfully saving the life of a 3-day liver free pig for the first time. It will significantly improve the success rate of treatment for patients with acute liver failure and establish the most comprehensive and effective liver function replacement therapy for liver failure patients.
Organ drug screening
The surgical removal of diseased organs for ex vivo feeding is the world's first human disease organ model, solving the problem of existing medical research models being "unrealistic" and becoming a powerful tool for disease research and new drug development. It is expected to reconstruct the theoretical and technological system of new drug evaluation, accelerate the process of innovative drug research and development in China, and promote the transformation of the international drug research and development market and tumor marker market.
Organ-Quarantine Thearpy
The pioneering organ isolation treatment technology provides precise treatment for diseased organs, ensuring that other organs are not affected by drug side effects, truly achieving the goal of "treating the head for the disease and treating the foot for the disease". At present, the world's first organ isolation protection treatment and the world's first targeted treatment for liver cancer have been successfully implemented. The breakthrough of this innovative therapy is expected to develop into one of the mainstream models for the treatment of organ diseases.
Organ transplant
Based on a multi organ maintenance system, the world's first ischemia free organ transplantation was successfully performed, achieving uninterrupted organ blood flow throughout the entire transplantation process. At present, more than 250 cases of ischemia free liver transplantation have been carried out clinically, and the world's first ischemia free kidney transplantation and heart transplantation have been successfully carried out. Organ transplantation has entered the era of "hot transplantation", and an article in the American Journal of Transplantation considers it a "milestone in the history of organ transplantation" and has been included in the "World Guidelines for Innovative Technology Applications in Organ Transplantation". The organ maintenance system has been selected as a key supported project by the National Medical Products Administration.
Organ teaching
The world's first "live organ" surgical training system, which separates and feeds the internal organs of slaughterhouses, transforms them into "sacred tools" for medical anatomy teaching and surgical training for surgeons. It has been applied and training bases have been established in many well-known hospitals across the country, greatly improving the training efficiency of laparoscopic surgeons and ensuring the safety of patients during surgery.
Organ research
Establishing a new scientific research instrument for organ dimension medical basic research, to achieve precise research on the physiological functions and pathological mechanisms of organs, and to explore the "dialogue" between organs in depth on this pure platform. It is expected to reconstruct the theoretical system of basic medicine through many original discoveries.
Organ donation
The invention of the "Organ Saver" device for heart death organ donation can successfully utilize organs that cannot be donated by previous methods, which is expected to double the source of organs and alleviate the problem of organ shortage.
